ABSTRACT
Thirty three patients [age 12-56 Y] with newly diagnosed acute lymphoblastic leuckaemia [A.L.L] who were admitted to Baghdad Teaching Hospital Jan 1994 and June 1995 were studied. Thirteen patients has Lymphomatous A,L,L and 20 patients did not show such features and served as the control group. Both groups received the same induction chemotherapy with Vincristine. Doxorubicine, and Prednisolone for 6 weeks. The rate of complete remission [C,R was 46% for the Lymphomatous A,L,L group and this difference was statistically significant [P < 0.05]
Subject(s)
Humans , Leukemia/drug therapy , Chemotherapy, Adjuvant/methods , Hematologic DiseasesABSTRACT
Clinical, haematological and bone marrow histo!ogical patterns were studied in a series of 68 Iraqi patients with chronic lymphocytic Leukaemia. The application of the two major clinical staging systems [namely the Rai and Binet systems] to the classification of patients in this series showed that the majority had an advanced stage at presentation [63.2% were Binet stage C [Rai stages III and IV]], Bone marrow histological patterns were diffuse in 51.5%, mixed in 32.3% and interstitial in 16.2%, while none were nodular. Such findings are quite different. from those reported from North America and Europe, Where early and Intermediate clinical stages and interstitial marrow histological patterns predominate. Furthermore, significant correlations between the marrow histological patterns and both Rai and Binet staging systems were found, a finding which is consistent with studies from Western countries